Prescription Drugs for Obesity

The FDA has approved several prescription drugs for obesity. Those available on the market include:

  • Dexedrine and other amphetamines
  • Ionamin and Adipex-P (phentermine), Sanorex (mazindol), Tenuate (diethylpropion), Prelu-2 (phendimetrazine) and other amphetamine derivatives
  • meridia (sibutramine).


FDA approved the drugs only for use with calorie-restricted diets. The drugs are "not magic pills," warns Leo Lutwak, M.D., Ph.D., of FDA's division of metabolism and endocrine drug products. "They don't work unless you make dietary and exercise changes."

These drugs are addictive and have the potential for abuse. They should be used only for a few weeks and they shouldn't be used in combination with each other or with other drugs for appetite control because such combinations have not been evaluated for safety.



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