Nerves and Fat or Thin
A study on worms shows that serotonin levels in the nervous system influence feeding and fat. Serotonin, a neurotransmitter, also acts independently to control eating and what your body does with those calories once they've been consumed, the study said.
The findings were published in the June issue of Cell Metabolism.
In the worms, serotonin affected feeding by involving nerve receptors not normally required for fat control. The byproducts of the signaling process ended up affecting the control of feeding behavior, Ashrafi said.
In the worms and in mammals, high serotonin levels are associated with fat reduction, while low serotonin levels lead to fat accumulation, the researchers noted. However, in the worms, when serotonin goes up, the worms desire to eat increases even as fat melts away. But in humans, high serotonin leads people to eat less and shed fat.
Serotonin's effects on fat and eating habits in the worms fit the nerve messenger's role as a sensory gauge of nutrient availability, the researchers said. When resources are scarce, worms build up their fat reserves and switch metabolic gears to save energy and direct nutrients to fat stores.
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